The list below includes software that is free for Linux and Windows systems.
| Software | Linux | Windows | Description |
|---|---|---|---|
| Accelrys Draw | W | Chemical drawing application that replaces ISIS/Draw. Includes support for IUPAC names, canonical SMILES strings, InChI strings. | |
| BKChem | L | W | 2D molecule editor written in Python. |
| ChemSketch | L | W | Chemical drawing package including tools for 2D structure cleaning, 3D optimization and viewing, InChI generation and conversion, drawing of polymers, organometallics, Markush structures, and IUPAC systematic naming capability. Best. |
| MarvinSketch | L | W | Java based chemical editor for drawing chemical structures, queries and reactions. |