Israel Science and Technology Directory

Biomedical Databases

The abbreviations listed on this page are common abbreviations that do not require further definition within an article. The source of this table is the Journal of Biological Chemistry - Instructions to Authors.

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Biochemical Abbreviations
AbbreviationDefinition
ABCATP-binding cassette, e.g., ABC transporter
Acacetyl
AIDSacquired immunodeficiency syndrome
ALSamyotrophic lateral sclerosis
AMP, ADP, ATPadenosine 5'-mono, di-, and triphosphates
ATPaseadenosine triphosphatase
β-galβ-galactosidase
BSAbovine serum albumin
cAMPcyclic AMP (adenosine 3':5'-monophosphate)
CDcircular dichroism
cGMPcyclic guanosine monophosphate
CHAPS3-(3-cholamidopropyl) diethyl-ammonio-1-propanesulfonate
ChIPchromatin immunoprecipitation
CMP, CDP, CTPcytidine 5'-mono-, di-, and triphosphates
CoAcoenzyme A
COSYcorrelated spectroscopy
CRISPR clustered regularly interspaced short palindromic repeats
cryo-EMcryo-electron microscopy
C-terminalcarboxy-terminal
d as in dADP, dTMP, etc.deoxy
DEADacronym for Asp-Glu-Ala-Asp, e.g., DEAD-box helicase
DMSOdimethyl sulfoxide
DNAdeoxyribonucleic acid
DNasedeoxyribonuclease
dsDNAdouble-stranded DNA
dsRNAdouble-stranded RNA
DTTdithiothreitol
EC50half-maximal effective concentration
ED50half-maximal effective dose
EDTAethylenediaminetetraacetate
EGTA[ethylenebis(oxyethylenenitrilo)]tetraacetic acid
ELISAenzyme-linked immunosorbent assay
EMelectron microscopy
EPRelectron paramagnetic resonance
FACSfluorescence-activated cell sorter/sorting
FAD, FADH2flavin-adenine dinucleotide and its fully reduced form
FITCfluorescein isothiocyanate
fMetformylmethionine
FMNriboflavin 5'-phosphate
FPLCfast protein liquid chromatography
FRETFörster/fluorescence resonance energy transfer
FTIRFourier transform infrared
GABAγ-aminobutyric acid
GalNAcN-acetylgalactosamine
GC, GLCgas chromatography, gas/liquid chromatography
GFPgreen fluorescent protein
GlcNAcN-acetylglucosamine
GMP, GDP, GTPguanosine 5'-mono-, di-, and triphosphates
G proteinguanine nucleotide–binding regulatory protein
GSH/GSSGglutathione and its disulfide form
Hepes or HEPES4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid
HIVhuman immunodeficiency virus
HPLChigh-performance/pressure liquid chromatography
IC50concentration giving half-maximal inhibition
ID50half-maximal infective dose
IDP, IMP, ITPinosine 5'-mono-, di-, and triphosphates
IgG, etc.immunoglobulin G, etc.
IRinfrared
kDa or Dakilodalton, dalton
KMMichaelis-Menten constant
LC/MS, LC-MSliquid chromatography/mass spectrometry
LD50half-maximal lethal dose
mAbmonoclonal antibody
MALDImatrix-assisted laser desorption/ionization
MDM2mouse double minute 2 homolog
Mes or MES2-(N-morpholino)ethanesulfonic acid
Mops or MOPS3-(N-morpholino)propanesulfonic acid
MRImagnetic resonance imaging
mRNAmessenger RNA
MSmass spectrometry/spectroscopy
mTORmechanistic/mammalian target of rapamycin
Na,K-ATPasesodium-potassium pump
NAD, NAD+, NADH nicotinamide-adenine dinucleotide and its oxidized and reduced forms
NADP, NADP+, NADPH nicotinamide-adenine dinucleotide phosphate and its oxidized and reduced forms
NF-κBnuclear factor κ-light-chain-enhancer of activated B cells
NMRnuclear magnetic resonance
NOEnuclear Overhauser effect/enhancement
NOESYnuclear Overhauser effect/enhancement spectroscopy
N-terminal amino-terminal
NMP, NTP, NDPnucleoside 5'-mono-, di-, and triphosphates
O-GlcNAcylation O-linked attachment of N-acetylglucosamine to proteins
ORFopen reading frame
PAGEpolyacrylamide gel electrophoresis
PBSphosphate-buffered saline
PCRpolymerase chain reaction
PDZcontraction of post-synaptic density protein 95, Drosophila disc large tumor suppressor, and zonula occludens-1, e.g., PDZ domain
PEGpolyethylene glycol
PETpositron-emission tomography
Piinorganic phosphate
Pipes or PIPESpiperazine-N-N'-bis(2-ethanesulfonic acid)
pKathe logarithm of the acid dissociation constant
Poly(dG)Poly(dC), etc.single-stranded DNA composed of polydeoxyguanylate, polydeoxycytidylate, etc.
Poly[d(A-T)], etc.double-stranded DNA composed of polydeoxyadenylate and polydeoxythymidylate, etc.
PPiinorganic pyrophosphate
RNAribonucleic acid
RNAiRNA interference
RNA-SeqRNA sequencing
RNaseribonuclease
rRNAribosomal RNA
RT-PCRreverse-transcription polymerase chain reaction
SAH/AdoHcyS-adenosylhomocysteine
SAM/AdoMetS-adenosylmethionine
SDSsodium dodecyl sulfate
siRNAsmall interfering RNA
SNPsingle-nucleotide polymorphism
TCAtrichloroacetic acid
TFAtrifluoroacetic acid
THFtetrahydrofuran
TLCthin-layer chromatography
TMP, TDP, TTPribosylthymine 5'-mono, di-, and triphosphates
TMStrimethylsilyl
TOFtime-of-flight
Tristris(hydroxymethyl)aminomethane
tRNAtransfer RNA
t1/2half-life
UDP-galactoseuridine 5'-diphosphate-galactose
UDP-glucoseuridine 5'-diphosphate-glucose
UMP, UDP, UTPuridine 5'-mono, di-, and triphosphates
UTRuntranslated region
UVultraviolet
Vmaxmaximum velocity
WTwildtype