Israel Science and Technology Directory

Biomedical Databases : Biochemical Abbreviations

The abbreviations listed on this page are common abbreviations that do not require further definition within an article. The source of this table is the Journal of Biological Chemistry - Instructions to Authors.

Also see: Amino acid abbreviations

To sort the list, click a column heading.

AbbreviationDefinition
ABC ATP-binding cassette, e.g., ABC transporter
Ac acetyl
AIDS acquired immunodeficiency syndrome
ALS amyotrophic lateral sclerosis
AMP, ADP, ATP adenosine 5'-mono, di-, and triphosphates
ATPase adenosine triphosphatase
β-gal β-galactosidase
BSA bovine serum albumin
cAMP cyclic AMP (adenosine 3':5'-monophosphate)
CD circular dichroism
cGMP cyclic guanosine monophosphate
CHAPS 3-(3-cholamidopropyl) diethyl-ammonio-1-propanesulfonate
ChIP chromatin immunoprecipitation
CMP, CDP, CTP cytidine 5'-mono-, di-, and triphosphates
CoA coenzyme A
COSY correlated spectroscopy
CRISPR clustered regularly interspaced short palindromic repeats
cryo-EM cryo-electron microscopy
C-terminal carboxy-terminal
d as in dADP, dTMP, etc. deoxy
DEAD acronym for Asp-Glu-Ala-Asp, e.g., DEAD-box helicase
DMSO dimethyl sulfoxide
DNA deoxyribonucleic acid
DNase deoxyribonuclease
dsDNA double-stranded DNA
dsRNA double-stranded RNA
DTT dithiothreitol
EC50 half-maximal effective concentration
ED50 half-maximal effective dose
EDTA ethylenediaminetetraacetate
EGTA [ethylenebis(oxyethylenenitrilo)]tetraacetic acid
ELISA enzyme-linked immunosorbent assay
EM electron microscopy
EPR electron paramagnetic resonance
FACS fluorescence-activated cell sorter/sorting
FAD, FADH2 flavin-adenine dinucleotide and its fully reduced form
FITC fluorescein isothiocyanate
fMet formylmethionine
FMN riboflavin 5'-phosphate
FPLC fast protein liquid chromatography
FRET Förster/fluorescence resonance energy transfer
FTIR Fourier transform infrared
GABA γ-aminobutyric acid
GalNAc N-acetylgalactosamine
GC, GLC gas chromatography, gas/liquid chromatography
GFP green fluorescent protein
GlcNAc N-acetylglucosamine
GMP, GDP, GTP guanosine 5'-mono-, di-, and triphosphates
G protein guanine nucleotide–binding regulatory protein
GSH/GSSG glutathione and its disulfide form
Hepes or HEPES 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid
HIV human immunodeficiency virus
HPLC high-performance/pressure liquid chromatography
IC50 concentration giving half-maximal inhibition
ID50 half-maximal infective dose
IDP, IMP, ITP inosine 5'-mono-, di-, and triphosphates
IgG, etc. immunoglobulin G, etc.
IR infrared
kDa or Da kilodalton, dalton
KM Michaelis-Menten constant
LC/MS, LC-MS liquid chromatography/mass spectrometry
LD50 half-maximal lethal dose
mAb monoclonal antibody
MALDI matrix-assisted laser desorption/ionization
MDM2 mouse double minute 2 homolog
Mes or MES 2-(N-morpholino)ethanesulfonic acid
Mops or MOPS 3-(N-morpholino)propanesulfonic acid
MRI magnetic resonance imaging
mRNA messenger RNA
MS mass spectrometry/spectroscopy
mTOR mechanistic/mammalian target of rapamycin
Na,K-ATPase sodium-potassium pump
NAD, NAD+, NADH nicotinamide-adenine dinucleotide and its oxidized and reduced forms
NADP, NADP+, NADPH nicotinamide-adenine dinucleotide phosphate and its oxidized and reduced forms
NF-κB nuclear factor κ-light-chain-enhancer of activated B cells
NMR nuclear magnetic resonance
NOE nuclear Overhauser effect/enhancement
NOESY nuclear Overhauser effect/enhancement spectroscopy
N-terminal amino-terminal
NMP, NTP, NDP nucleoside 5'-mono-, di-, and triphosphates
O-GlcNAcylation O-linked attachment of N-acetylglucosamine to proteins
ORF open reading frame
PAGE polyacrylamide gel electrophoresis
PBS phosphate-buffered saline
PCR polymerase chain reaction
PDZ contraction of post-synaptic density protein 95, Drosophila disc large tumor suppressor, and zonula occludens-1, e.g., PDZ domain
PEG polyethylene glycol
PET positron-emission tomography
Pi inorganic phosphate
Pipes or PIPES piperazine-N-N'-bis(2-ethanesulfonic acid)
pKa the logarithm of the acid dissociation constant
Poly(dG)Poly(dC), etc. single-stranded DNA composed of polydeoxyguanylate, polydeoxycytidylate, etc.
Poly[d(A-T)], etc. double-stranded DNA composed of polydeoxyadenylate and polydeoxythymidylate, etc.
PPi inorganic pyrophosphate
RNA ribonucleic acid
RNAi RNA interference
RNA-Seq RNA sequencing
RNase ribonuclease
rRNA ribosomal RNA
RT-PCR reverse-transcription polymerase chain reaction
SAH/AdoHcy S-adenosylhomocysteine
SAM/AdoMet S-adenosylmethionine
SDS sodium dodecyl sulfate
siRNA small interfering RNA
SNP single-nucleotide polymorphism
TCA trichloroacetic acid
TFA trifluoroacetic acid
THF tetrahydrofuran
TLC thin-layer chromatography
TMP, TDP, TTP ribosylthymine 5'-mono, di-, and triphosphates
TMS trimethylsilyl
TOF time-of-flight
Tris tris(hydroxymethyl)aminomethane
tRNA transfer RNA
t1/2 half-life
UDP-galactose uridine 5'-diphosphate-galactose
UDP-glucose uridine 5'-diphosphate-glucose
UMP, UDP, UTP uridine 5'-mono, di-, and triphosphates
UTR untranslated region
UV ultraviolet
Vmax maximum velocity
WT wildtype