Israel Science and Technology Directory

Directory of agriculture companies.

Directory of companies that manufacture medical devices and systems.

Algae-derived products for nutraceutical and cosmetics industry. Astaxanthin, a red pigment carotenoid found in algae and aquatic animals that functions as an antioxidant (free-radical scavenger). Feed additive to impart coloration to salmon and trout.

Site-specific stents and stent delivery systems with applications in the urinary, gastrointestinal and respiratory tract for use in malignant and benign obstructions. Biliary stent. Prostatic stent. Ureteral stent.

Molecular tools for the neuroscience community. Molecular tools for calcium, sodium and potassium channels, channel blockers, modulators, antibodies. Inhibitors for PKC, protein phosphatase, tyrosine kinase. Antibodies and toxins.

Analytical and microbiological tests for the pharmaceutical, cosmetics, food, chemical, biological, environmental and agricultural industries.

Targeted therapy based on the identification of genes that are highly expressed only in tumors. The regulatory sequences of these genes (e.g. H19) are used to express a toxin gene exclusively within tumor cells, enabling targeted tumor-cell destruction.

Aposense for PET, SPECT and MRI based clinical molecular imaging of apoptosis. Therapies based on the targeting of therapeutic agents to apoptosis inflicted tissues.

Cytogenetics, automated spectral karyotyping, FISH probes and imaging. SKY displays chromosomes in unique colors, identifies chromosomal aberrations indicative of cancer, birth defects and genetic problems. Meta scan for Metaphase spreads.

Registration of pharmaceuticals (drugs, cosmetics, nutritional supplements) and medical devices according to the requirements of the Israeli Ministry of Health. Certified with ISO 9001 standard. Strategic consulting.

Product and process development, GxP, validation, quality control services. Consultancy for pharmaceutical, biotechnology, medical device companies, cosmetics and food industries.

Manufacturer of biopharmaceuticals based on genetic engineering employing both bacterial fermentation and mammalian cell culture technologies. Products include recombinant human growth hormone (somatropin for injection or hGH) and BioLon.

Drug development company. Development of novel compounds for the treatment of neurological disorders including schizophrenia, neurodegenerative disease and cancer.

Clinical data managment. Biostatistics. Clinical programing. Medical writing.

Drugs to treat inflammatory diseases and cancer by targeting immune and tumor cell migration, via chemokines. BKT104 targeting production of TNF-Alfa. BKT140, a CXCR4 chemokine receptor antagonist for treatment of tumor growth and metastasis.

Animal cell culture products, serum-free media and serum substitutes, human cytogenetics products. Distributor of imported chemicals, biochemicals and molecular biology products.

Development of universal multi-season / multi-strain, intranasal flu vaccine. Technology utilizes a combination of conserved epitopes derived from the influenza virus possessing strong immunogenic capabilities.

Turnkey design and construction of pharmaceutical and biotechnological (API) plants. HVAC and clean rooms, sterile and aseptic filling and packaging lines, Cleaning-in-place and sterilization-in-place (CIP/SIP). Systems comply with USP and EU standards.

Cell therapeutic products, NurOwn, for treatment of neurological diseases. Developing NTF cells from the patient's own bone marrow to treat Parkinson, ALS, and spinal cord injury.

Expandable Fixion Intramedullary Nailing Systems for fracture fixation. Expandable B-Twin Spinal System for use in lumbar spinal fusion. Quantum carbon fiber reinforced composite material for the treatment of fractures of the long bones.

Plant-based technology for mass production of recombinant human Type I collagen (rhCollagen), identical to the collagen produced by the human body. Applications include BioInks for 3D bioprinting of organs, tissues and scaffolds as well as products aimed at aesthetic medicine, orthopedics, and wound care.

Skyline, a data management software platform to manage and analyze Pharmaceutical, Chemical and Biotechnology process information from conception to manufacturing and clinical applications. Generica QMS for Life Sciences is an integrated and fully customizable Quality Management System. Extensive experience with FDA 21 CFR Part 11 compliance.

Manufacturer of contact lenses, lens solutions and accessories. Multifocal, toric, therapeutic, cosmetic, prosthetic, disposable and gas permeable contact lenses. Colored lenses. Soft K Keratoconus lenses.

Drugs for neurocognitive and neurodegenerative disorders. CP201 for Cognitive Impairment Associated with Schizophrenia (CIAS).

UV transilluminators, gel imaging systems.

Manufacture of prescription, generic and over the counter (OTC) pharmaceutical products. Analgesic, anti-inflammatory, antibiotic, antihistamine, anti-hypertensive, antidepressant, diuretic drugs. Multi-vitamin supplements. Oral contraceptive.

Medical diagnostics system for testing body fluids and cells utilizing a flow cytometer (FC). Kits for analysis of semen, IVF success prediction, hormone levels, genital infections, and immuno-infertility.

Manufacturing of injection-molded plastic disposable medical devices for OEM use in critical care unit, I.V. sets, cardiovascular therapy and hemodialysis bloodline sets. Product lines include stopcocks, manifolds and needleless injection systems.

In silico drug discovery platform based on proprietary 3D computational chemistry technologies specializing on G-protein coupled receptors (GPCRs) to identify novel drug-like compounds that bind specifically to GPCR targets in affinity assays.

Biologically active, natural products isolated from microorganisms. Products include A23187, actinomycin D, aflatoxin, anisomycin, cytochalasin, mycotoxins, inhibitors of protein kinases A, C, G, antibiotics, immunosuppressive agents, staurosporine.

Ophthalmic, dermatological and skin-care preparations: Genesis Minerals sunscreens, shampoos, body lotions, Anti Acne Package, antiseptic wet tissues, Kamil Blue - Baby Skin Care products.

Solumer - Nanotechnology for drug re-engineering and production of water-soluble compounds. Soluble anti-cancer and anti-infective drugs, including Itraconazole, Azithromycin, Clarithomycin, Taxol, Cannabidiol in water based solutions.

Manufacturer of citric acid, citrates, food phosphate salts and various food ingredients.

Medical genetics laboratory. Genetic testing for prenatal diagnosis. Screening to identify genetic compounds associated with personalized medicine. DNA testing for forensic purposes. Identification of chromosomal changes using CGH typegenetic chips.

Biomarkers for autoimmune diseases using glycan molecules as probes via proprietary GlycoChip technology. IBD differential diagnosis (Chron's disease vs. Ulcerative colitis). Multiple sclerosis assay.

Manufacturer and marketer of prepared media and microbiological diagnostic kits. Systems for the transport and storage of microorganisms, including salmonella, shigella, campylobacter, vibrio spp, pneumococci and anaerobic microorganisms.

Manufacturer of nutraceuticals and food supplements. Products include: Prostacal alleviates symptoms of benign prostatic hyperplasia. FluVir an anti-influenza syrup.

AnapnoGuard solution provides tools to minimize complications in intubated and ventilated patients. AnapnoGuard monitors air leakage from the lungs around the airway cuff, based on continuous measurement of CO2 levels in the subglottic space, above the cuff.

Manufacturer of proprietary drugs-of-abuse forensic testing products. Drug-lab quality identification field kits (substance only) for the detection of marijuana, hashish, ecstasy, cocaine, crack and heroin. Suitable for use by police field units.

Biopharmaceuticals. Specialty plasma derivatives, specific and general immune globulins produced using proprietary chromatographic separation and purification methods. Anticoagulant heparin and antagonist. Parenteral electrolyte solutions.

Manufacturer of soy lecithin phosphatidylserine for neurological diseases and as dietary supplements for enhancing foods and beverages.

Natural products based on the carotenoid antioxidant Lycopene extracted from tomatoes.

Manufacture of dental implants made of biocompatible Titanium alloy. Surface roughened for long-lasting osseointegration. Twist drills. Trephine burrs. Surgical tools. Prosthetic instruments. Osteotome set. MGUIDE virtual implant planning.

Manufacturer of powdered food products for human consumption, pet foods and veterinary milk substitutes.

Materna baby food and milk products.

Debrase Gel Dressing (DGD) enzymatic product used for the debridement of burn wounds. DGD dissolves the eschar within 4 hours of treatment providing a fast and safe alternative to surgery or non-surgical methods.

Manufacture, development, production, distribution and marketing of pharmaceuticals (Rx and OTC), special nutritional supplements and medical devices.

Miloubar animal feeds. Milouof poultry growing, processing and marketing of poultry products.

Painless microneedle devices for drug delivery and diagnostics. NanoPump - Low-cost, disposable, biocompatible product for controlled release of large molecules, including therapeutic proteins such as insulin, antibodies and vaccines.

Intranasal powder products based on a unique microsphere technology designed for rapid drug delivery, ease of use, non-invasiveness, and safety. Intranasal Epinephrine (NS –002) for severe allergic type 1 reaction. Powder sprayed into the nose and sinuses forms an acidic gel layer that provides mechanical and chemical protection against viruses, Under trial for COVID-19.

Small molecule drug research and development in the field of central nervous system (CNS) disorders. Circadin- prolonged-release melatonin.

Urinary tract stone retrieval and entrapping devices. Medical devices based on Nitinol Alloy (NiTi) characterized by super-elasticity and shape memory capabilities. Applications include urology, cardiology and surgical medical devices.

Immunodiagnostic kits. DipStreak and ChromoStreak for diagnosis of urinary tract infections. NovaStreak for detection of microorganisms in food and dairy products. Uni-Sep for lymphocyte isolation. Extracellular Matrix (ECM) Coated Plastic Ware.

Technology that identifies tumor specific driver mutations based on a functional assay that detects disregulated translocation of mutated signaling proteins to the nucleus. Assay can measure impact of a drug on a specific tumor.

Peptide based active pharmaceutical ingredients for the pharmaceutical industry. Calcium regulators, calcitonin, Parathyroid Hormone. Vasopressin analog Desmopressin. Somatostatin. LHRH analogs Leuprolide, Goserelin, Buserelin, Triptorelin.

NutriMore: soy protein and fiber fraction from Non GMO soy beans; used in baked goods. NutriFree+: Gluten free soy protein and fiber fraction; used in GLUTEN FREE FOODS to replace simple carbohydrates. NutriTex for snack foods and as additives.

Corrective eye drop to treat presbyopia as an alternative to reading glasses. Presbyopia, the inability to focus on near objects, typically occurs after the age of 40 and affects more than 1.8 billion people worldwide.

Wrist pulse oximeter without fingertip probe. Provides SpO2 and pulse rate readings from wrist. Application monitoring patients with heart disease and epilepsy.

Laboratory services for histopathology and cytopathology. Processing and interpretation of biopsies, operative specimens, fine needle aspirations (FNA) and cytological preparations. Gynecologic PAP smears. Complies with Good Laboratory Practice (GLP).

Design of novel peptide drug candidates by artificial intelligence based on the 3D structure of the target protein. The company designs Linear peptides, Helical peptides, Cyclic peptides with high serum stability and D-PEP – Peptides with D-amino-acids which are less susceptible to proteolytic cleavage.

Perflex develops new formulas of high performance, biocompatible thermoplastics for injection molding and tools, to simplify the working process in dental laboratories. Acryfree - Non-allergenic elastic acrylic PMMA for dentures, fixable and relinable with acrylic resin. Thermofix - Biocompatible, unbreakable thermoplastic for instant bite registrations and immediate impressions.

Manufacturer of a wide range of products including cardiovascular and dermatological pharmaceuticals, antibiotics, Ethical topical pharmaceuticals. Formerly Agis.

GLP-compliant contract research organization (CRO) that provides early-stage discovery, pre-clinical, early-development services for small and medium-size start-ups. In vivo studies conducted in-house laboratory and animal facilities.

Biomaterials, Hyaluronic Acid (HA) and fibrinogen based hydrogels useful for clinical applications. Proprietary growth factors with enhanced selectivity and biological activity. Stem and progenitor cell isolation, expansion and differentiation.

Bulk production of E. coli-derived recombinant human cytokines and growth factors as well as monoclonal anti-cytokine and chemokine antibodies.

Molecular diagnostics and research services including: Next generation DNA sequencing, identification of unknown genetic polymorphisms, pharmacogenetic testing, epigenetics. Pronto Diagnostic Kits for detecting polymorphisms in DNA sequences associated with genetic diseases such as Cystic Fibrosis.

Proprietary plant cell culture and bioreactor system for efficient, large-scale production of complex human therapeutic proteins, monoclonal antibodies, Glucocerebrosidase enzyme replacement for Gaucher's Disease and other recombinant proteins.

Genomics-based drug discovery and development. BiFAR platform for bioinformatics-based target gene selection. Current focus on cancer, fibrotic diseases, ischemic diseases, brain disorders, bone and cartilage disorders, diabetes.

Manufacturer of Over-the-Counter medicines (OTC), generic drugs, antibiotics, etc. Kalgaron for sore throat relief. Fluconazole and lansoprazole. Drugs for diseases of the digestive tract and treatment of pain.

Enzymes for the textile, food, animal feed industries. Products include acid and neutral cellulase, alfa amylase, catalase, lipase, pectinase, protease. Microbial rennet milk clotting enzyme.

Development of late clinical-stage, proprietary drugs for the treatment of gastrointestinal diseases. Drugs under development include oral combination therapy for Helicobacter pylori infection, Crohn's disease, acute gastroenteritis and gastritis.

Biodegradable hydrogels for local repair of damaged cartilage and bone. Gelrin for restoration of normal joint function by regenerating hyaline cartilage and void filling matrix for bone regeneration designed to be used in osseous injuries.

Portable survey meters for alpha, beta and gamma radiation, hydrazine, stable isotopes (O-18), sapphire domes and windows, radioactive products for nuclear medicine, radiopharmaceuticals, labeling services.

Manufacturer of medical furniture. Over 100 models of hospital beds, stretchers and trolleys, for intensive care, emergency/casualty, maternity, geriatrics, orthopedic, internal, pediatric and home care.

In vitro medical diagnostics testing for sexually transmitted diseases (e.g., Chlamydia), viral diseases, urinary and respiratory infections.

Sintered diamond instruments for dental laboratories designed for grinding, cutting and polishing precious, semi-precious and non-precious metals and Titanium. Instruments for use on porcelain, acrylic and gypsum.

OLO - Instrument for complete blood count (CBC). Parasight - Quick and accurate detection of malaria using digital fluorescent microscopy and computer vision algorithms.

Broadest range of biochemicals, organic chemicals, chromatography products and diagnostic reagents.

Manufacturer, marketer and supplier of surgical dressings, medical textiles, OTC ointments, and sterile solutions for disposable products for hospitals and medical institutions. Gowns, patient covers, equipment covers.

Research and development services in the fields of biochemistry and histology. Cell free and cell based assay development. High Throughput Screening HTS format. Custom histological service starting from tissue collection to histopathological evaluation.

Sol-gel nanotechnology for encapsulation of active ingredients in nano size glass (silica) matrices and nanospheres. UV-Pearls safe and inert sunscreen and cosmetics. Acti-Pearls benzoyl peroxide antibacterial acne medication without irritation.

Solio Alfa Plus developed to reduce chronic pain. It uses specific wavelengths and bipolar RF to stimulate the body’s healing mechanisms and increase blood circulation, drawing oxygen and nutrients to the afflicted area. Solio Alfa Plus is an FDA Cleared home-use device.

Manufacturer of SonoMask - a reusable washable mask. It provides two-sided protection, and neutralizes over 99% of COVID-19​. Sonomask comes in three sizes: small, medium and large. The technology utilizes ultrasonic energy to infuse textiles via a sustainable process, giving them wash-durable, antiviral, anti-microbial, anti-fungal and anti-odor properties.

Products for molecular biology research with DNA synthesis facility in Jerusalem to produce custom oligos. Kits for Real-Time PCR, custom probes, siRNA, peptides, antibodies and more.

Microencapsulated vitamins A, E and F suitable for cosmetic formulations providing increased stability of active principles. Microencapsulated natural oils. Stable derivatives of vitamin C.

Pharmaceutical company with a wide range of products, from over-the-counter analgesics and vitamins to injectable anti-cancer drugs.

Distributor of diagnostics and laboratory systems, hygiene and food testing biomedical products in Israel.

Global pharmaceutical company specializing in the development, production and marketing of generic and proprietary branded pharmaceuticals and active pharmaceutical ingredients. Copaxone for the treatment of Relapsing- Remitting Multiple Sclerosis.

Over-the-counter pharmaceuticals. Dermatological preparations, creams and ointments. Non-steroidal anti-inflammatory drug (NSAID) analgesics for rheumatology. Some example products: Acnetrim, Betacorten, Fungimon, Celcox, Diatrim, Dentix.

Autoclaves, and sterilization equipment for the medical, dental, pharmaceutical, bio-technology, and surgical markets. Ultrasonic cleaning systems.

Manufacture of branded generic drugs for cardiovascular medicine, neurology, psychiatry, gastroenterology, and macrolide antibiotics.

Innovative therapies in dermatology. AMZEEQ (minocycline) topical foam for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in adults and pediatric patients. ZILXITM (minocycline) topical foam, a tetracycline-class drug indicated for the treatment of inflammatory lesions of rosacea in adults.

Patented FreshCode label that triggers a value change in the displayed barcode as a result of temperature change. Barcode can be read by barcode reader and Android smartphones. FCMS Hand held barcode readers. Frozen or cold product monitoring.

Products at pre-clinical stage for prevention of progression of atherosclerosis in patients. Gene therapies targeted to the vascular wall endothelial cells, for both cancer and ischemic disease applications.

Novel therapeutics to treat life-threatening infectious diseases based on human monoclonal antibodies (hMAbs) and small molecule drugs. Developing anti-HBV and anti-HCV therapeutics.

XenX - prevents the common problem of migration of stone fragments during ureteroscopic lithotripsy. Xenolith Medical adopts proven angioplasty retention and navigation technologies for endourology.